Endocrine Abstracts

Background: Chronic opioid use may lead to adrenal insufficiency (AI) due to suppression of the hypothalamic-pituitary-adrenal axis. We aimed to determine incidence of AI and mortality in patients treated with chronic opioid therapy in a standardized geographically well-defined population.Methods: In this population-based cohort study we assessed the standardized incidence rate of first time met chronic opioid use and adrenal insufficiency in adult resid...

Background: Diagnosing adrenal insufficiency (AI) often requires complex multi-step testing which can be expensive and time consuming. In this study, we evaluated the diagnostic performance of baseline dehydroepiandrosterone sulfate (DHEAS) level in identifying patients with AI.Methods: A single-center retrospective cohort study was performed of patients who underwent Cosyntropin stimulation testing (CST) between 2005 and 2023 and had a baseline DHEAS le...